June, 2011 – A study by researchers at Harvard Medical School in Boston, US, led by Raif Geha, has generated data in a mouse model which supports the idea that the immune cells in the gut (T cells), are also responsible for atopic dermatitis.
Sufferers from atopic dermatitis often have food allergies, and skin contact with food allergens can worsen their dermatitis. The research found that T cells are sensitised by exposure to food allergens in the gut, and skin contact with food allergens can reprogram the gut-homing T cells into skin-homing T cells which then mediate allergic skin inflammation.
This study was reported in The Journal of Clinical Investigation.
This report was shared with us by the informational website, Skins Matter. Foods Matter, FreeFrom Foods Matter and Skins Matter are entirely independent informational websites and allergy portals which grew out of a monthly printed magazine. The magazine was started some 20 years ago by Michelle Berriedale-Johnson, a food historian, food journalist and ex-caterer, whose small son was diagnosed with a dairy intolerance. Visit www.foodsmatter.com to read more.